DNA ‘enhancements’ may solve JonBenet Ramsey killing 25 years later

Boulder police provided an update in the infamous unsolved mystery Monday, saying investigators have processed more than 1,500 pieces of evidence in the 6-year-old’s slaying.

JonBenet was found dead in the basement of her family’s home on Dec. 26, 1996, and an autopsy revealed she had been strangled.

The investigation has included the analysis of nearly 1,000 DNA samples as of this month, and “multiple suspects” have been compared for possible matches thanks to significant advances in DNA technology, department officials said.

Boulder police are also working with the Colorado Bureau of Investigation on “future DNA advancements” to hopefully make a break in the case that has long stymied detectives.

"Thanks to the huge advances in DNA technology, multiple suspects have been run through the system to check for matches," police in Boulder, Colo., say in a statement marking the anniversary.

The Colorado Bureau of Investigation has updated more than 750 reference samples in the case using current DNA technology. "That DNA is checked regularly for any new matches," police say.